B12 Methylcobalamin - 60 Capsules | Pure Encapsulations

Verifiable Science

Vitamin B12 is an important cofactor for energy metabolism. It works with folate in the methylation pathway, which supports healthy homocysteine metabolism in the synthesis of S-adenosyl-methionine (SAMe), an important methyl donor.1

As such, it supports methylation for key biochemical reactions occurring in blood cells, neurons, the vasculature and many other tissues.2

Through this pathway, vitamin B12 enables proper red blood cell formation, neurological function and DNA synthesis.3

The activated and methylated form methylcobalamin is the primary form found in the cytosol of cells and is the predominant active isomer in the bloodstream. By promoting SAMe production, methylcobalamin maintains healthy cell development, including the formation of red blood cells.4

References

1. Schnyder G, et al. JAMA.2002 Aug 28;288(8):973-9.
2. Yaqub BA, et al.Neurol Neurosurg. 1992;94(2):105-11.
3. van Asselt DZ, et al. J Gerontol A Biol Sci Med Sci.2001 Dec;56(12):M775-9.
4. Huskisson E, et al. J Int Med Res..2007 May-Jun;35(3):277-89.