L-Ornithine-L-Aspartate - 100g | Allergy Research Group


Promotes Healthy Ammonia Clearance and Liver-Supportive Nitrogen Metabolism*


L-Ornithine-L-Aspartate (LOLA) supports healthy nitrogen metabolism by promoting the natural detoxification of ammonia through the urea cycle and glutamine synthesis pathways.* This clinically relevant formula helps maintain liver function, ammonia clearance, and overall metabolic balance, particularly during periods of increased nitrogen stress.*


How It Works

L-Ornithine activates carbamoyl phosphate synthetase, the rate-limiting enzyme of the urea cycle, enhancing the conversion of ammonia to urea in periportal hepatocytes for excretion.*[1]• L-Aspartate serves as a substrate in transamination reactions and contributes to glutamine synthesis, aiding in ammonia removal via non-urea pathways.*[3]• Glutamine Synthetase Activation in perivenous hepatocytes, skeletal muscle, and brain tissue facilitates an additional mechanism for reducing circulating ammonia.*[3]• Clinical Research supports the use of oral LOLA in improving ammonia metabolism and mental state, especially in individuals with hepatic metabolic burden.*[4]• Meta-Analysis Findings indicate that LOLA supplementation significantly supports detoxification pathways.*[4,5]

Who It’s For

Designed for individuals seeking targeted support for ammonia clearance and liver-related nitrogen metabolism, or those seeking to ease metabolic stress, support a high protein diet, or support detoxification.*


Special Features

Each serving delivers 3 grams of high-quality LOLA in an easy-to-use powdered format, allowing flexible dosing and alignment with clinical trial protocols.*

Ingredients

Active IngredientsPer 1 rounded teaspoon% NRV*
L-Ornithine-L-Aspartate3 g-
*NRV = Nutrient Reference Value according to Regulation (EU) No 1169/2011
- = Nutrient Reference Value not established

Important Information

Warning:

  • If you are pregnant or breastfeeding, have any health condition or are taking any medication, consult your healthcare practitioner before use.

Storage:

  • Store in a cool, dry place, tightly capped, away from light.
  • Keep out of the reach of children.
  • Use only if safety seal is intact.
  • Variations in product color may occur.

Dosage & Storage Information

As a dietary supplement, 1 rounded teaspoon one or two times daily, or as directed by a healthcare practitioner.