L-Ornitina-L-Aspartato - 100g | Allergy Research Group

Promotes Healthy Ammonia Clearance and Liver-Supportive Nitrogen Metabolism*

L-Ornithine-L-Aspartate (LOLA) supports healthy nitrogen metabolism by promoting the natural detoxification of ammonia through the urea cycle and glutamine synthesis pathways.* This clinically relevant formula helps maintain liver function, ammonia clearance, and overall metabolic balance, particularly during periods of increased nitrogen stress.*

How It Works

L-Ornithine activates carbamoyl phosphate synthetase, the rate-limiting enzyme of the urea cycle, enhancing the conversion of ammonia to urea in periportal hepatocytes for excretion.*[1]• L-Aspartate serves as a substrate in transamination reactions and contributes to glutamine synthesis, aiding in ammonia removal via non-urea pathways.*[3]• Glutamine Synthetase Activation in perivenous hepatocytes, skeletal muscle, and brain tissue facilitates an additional mechanism for reducing circulating ammonia.*[3]• Clinical Research supports the use of oral LOLA in improving ammonia metabolism and mental state, especially in individuals with hepatic metabolic burden.*[4]• Meta-Analysis Findings indicate that LOLA supplementation significantly supports detoxification pathways.*[4,5]

Who It’s For

Designed for individuals seeking targeted support for ammonia clearance and liver-related nitrogen metabolism, or those seeking to ease metabolic stress, support a high protein diet, or support detoxification.*

Special Features

Each serving delivers 3 grams of high-quality LOLA in an easy-to-use powdered format, allowing flexible dosing and alignment with clinical trial protocols.*